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Findings from a multi-center, international clinical trial reported by a Cleveland Clinic physician show that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes

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In the following years long acting, once weekly injected GLP-1 receptor agonists were approved (once-weekly exenatide, dulaglutide, albiglutide, semaglutide)