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What Did the Study Conclude

Although the data in this study cannot be extrapolated directly to humans, it does shed some light on potentially important physiologic effects of the medication. The decrease in lean mass with GLP-1 use was associated with a lesser decrease in skeletal muscle mass and a greater decrease in the size of metabolically active organs such as the liver

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Patients with a history of medullary thyroid carcinoma or multiple endocrine neoplasia should avoid these medications, but most people with thyroid conditions can safely use them