doi: 10.1161/circulationaha.121.054360 Redd, Meredith A., Scheuer, Sarah E., Saez, Natalie J., Yoshikawa, Yusuke, Chiu, Han Sheng, Gao, Ling, Hicks, Mark, Villanueva, Jeanette E., Joshi, Yashutosh, Chow, Chun Yuen, Cuellar-Partida, Gabriel, Peart, Jason N., See Hoe, Louise E., Chen, Xiaoli, Sun, Yuliangzi, Suen, Jacky Y., Hatch, Robert J., Rollo, Ben, Xia, Di, Alzubaidi, Mubarak A
Additionally, the interplay between biochemical and mechanical factors influences post-translational modifications of collagen, such as hydroxylation and crosslinking (mediated by lysyl oxidase), which further bolster tensile strength
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Theres also an important caveat about early treatment