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Regional Disciplinary Medical Board: vitamin B12 cannot be overdosed In 2009, the Regional Disciplinary Medical Board in Eindhoven stated very clearly that an overdose is not possible: There can be no question of an overdose of hydroxocobalamin, as the excess is excreted in urine by the kidneys and therefore cannot accumulate in the body

Stomach or gut problems Various problems of the stomach or gut can be a cause of B12 deficiency

If the vial is a bacteriostatic preparation (containing benzyl alcohol), it can be stored and accessed for up to 28 days after the initial puncture, provided it is kept under proper storage conditions

If it has been warm (above 25 degrees Celsius) for more than 24 hours, assess the situation carefully