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The PAPST1 is a specific transporter of PAPS which acts through an antiport mechanism with PAP as the exchange substrate, thus providing the cytoplasm with activated sulfate and transporting back the toxic by-product of sulfation reaction to chloroplasts

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The active indications for CagriSema include Diabetes Mellitus, Type 2, Obesity, Liver Diseases (Alcoholic), Chronic Kidney Diseases, and Overweight.

qPCR efficiency was between 98% and 102% and the correlation coefficient was over 0.97 for each gene