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[5] It has been hypothesized to act through GH-mediated pathways on the osteoblasts (bone-forming cells), possibly leading to increased proliferation, development, and differentiation of the osteoblasts

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Endocrinology (2002) 7

Complementary Duration Profiles: Baseline Elevation Plus Pulsatility A critically important feature of the triple blend is that its three components operate across distinctly different timescales and these different timescales are precisely complementary to the physiological pattern of GH secretion that researchers wish to study and understand