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I also consider the potential role of glutathione in the metabolism of unsymmetrical bisacridines, a novel prosperous class of anticancer compounds developed in our laboratory

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Notably, the hepsin / mice exhibited a more pronounced increase in ROS levels after thioacetamide treatment compared with wild-type mice, which aligned with our hypothesis that hepsin / mice experience heightened ROS stress in the early stages of APAP exposure due to their elevated expression of GJ proteins (Fig