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Sattar N, Lee MM, Kristensen SL, Branch KR, Del Prato S, Khurmi NS, et al

By binding to ER in endothelial cells, estrogens induce nitric oxide (NO) release, consequently producing vasodilation (Penotti et al., 1996), and the impedance of this flow appears to be reduced after starting hormone (estrogen) replacement therapy (HRT) ( Estrogens and Neurodegenerative Diseases Experimental and clinical data suggest that estrogens have protective effects against neurodegenerative diseases (Kumar et al., 2010

Cells regulate the formation of specific retinoid isomers depending upon the cellular action required