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doi: 10.1016/j.celrep.2019.07.107 94 YangJZhouYLiYHuWYuanCChenSet al

Chlorotoxin (36 AAs), derived from the venom of the scorpion Leiurus quinquestriatus, is one of these peptides that bind specifically to these channels [117] (Fig

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Although stress and inflammation increase KYN availability via the activation of IDO and TDO, downstream flux through the KP is critically determined by the activity of KAT and KMO