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The combination hypothesis is that addressing both vascular/mucosal protection (BPC-157 territory) and cellular motility required for tissue remodeling (TB-500 territory) may produce better outcomes than either alone, though this needs study-specific verification

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Lamellipodia are modulated by RhoA and other Rho-GTPases, impacting actin polymerization, and the authors showed inhibition of RhoA activity by IIAMD

The levels of both GSSG and GSSP are greater during periods of oxidative stress and the ratio of GSSG and/or GSSP to GSH have often been used as biomarkers of oxidative stress 34