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Blood-Brain Barrier Research Experimental studies investigated whether DSIP or modified analogues crossed blood-brain and blood-cerebrospinal-fluid barriers

Other amino acids, such as Lysine and Branched-Chain Amino Acids (BCAAs) with leucine, isoleucine, and valine, may also be of interest for the synthesis of active molecules

10.1016/j.blre.2007.05.002 Blood Rev

We use a modified form of AP designed by Beckwith and colleagues (Figure 3A) suggested a modest rise (~ 15%) in mean activity among replicate samples, but the sample-to-sample variation was large enough that statistical significance was not achieved ( p = 0.57)