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Recent results from the DARE-ESKD Phase 1 trial (NCT05343078), on Pharmacokinetics and Dialyzability of Dapagliflozin in Dialysis Patients including a total of 7 patients (2 on peritoneal dialysis) have shown that dapagliflozin was well tolerated, slightly dialyzable, and had non-accumulating pharmacokinetic properties35 (Table 2)

Lower fluid intake may also reduce regular bladder flushing, which can increase the risk of urinary tract infections (UTIs) in some individuals

Thyroid Autoantibody Screening in Pregnancy The detection of thyroid antibodies before or early in pregnancy can predict the development of pregnancy loss, the need for thyroxine replacement therapy during pregnancy, and the onset of post partum thyroiditis [117]

Endocr J (2003) 50(3):2719.10.1507/endocrj.50.271 143 NguyenNQDebreceniTLBambrickJEChiaBWishartJDeaneAMet alAccelerated intestinal glucose absorption in morbidly obese humans: relationship to glucose transporters, incretin hormones, and glycemia