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MMPs normally regulate collagen degradation, with MMP-1 specifically implicated in the initiation of collagen fragmentation. A 2024 study found that elevated MMP-1 levels contribute to aging skin, causing in mice: A 2016 study showed that GHK-Cu significantly increased gene expression of MMP-1 and MMP-2 at the lowest concentration. Researchers attributed this as one mechanism by which the peptide increased collagen and elastin production

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IOSR Journal of Pharmacy 9(7):8088 Albrahim T, Robert A (2020) Renal protective effects of grape seed extract treatment against Eltroxin-induced hyperthyroidism, kidney damage, and oxidative stress in male mice

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