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"GLP-1 medications have transformed the treatment of diabetes and obesity, but they can also increase the risk of muscle loss," said Rebecca Gottlieb, Ph.D, Vice President of Advanced Sensor Technologies at Biolinq and lead author of the study

Research has confirmed that inhibiting polyamine biosynthesis with the ornithine decarboxylase inhibitor -difluoromethylornithine significantly mitigates increased BBB permeability, Evans blue extravasation, and brain tissue water content in models of cerebral ischemia (102)

And for long-term management, a combination of therapy, lifestyle changes, and (when appropriate) medication can dramatically reduce both the frequency and intensity of episodes