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Contraindications include personal or family history of medullary thyroid carcinoma or MEN 2 syndrome, pancreatitis history, severe GI or kidney disease, pregnancy, and breastfeeding

Training for a 5K, increasing strength milestones, or improving flexibility gives you targets to work toward after the scale has stopped being your primary metric

However, prior to March 2018, the Threshold Substances regime did not allow for such an adjustment to be made, and consequently several athletes were banned when they should not have been (and would not have been, had the adjustment in question been made to their laboratory results)

Poor sleep disrupts hormones that regulate appetite (increasing ghrelin and decreasing leptin), whilst chronic stress elevates cortisol, which promotes abdominal fat storage