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DAC vs No-DAC Selection This is the single biggest variable

Tension is a big factor in wound dehiscence and hypertrophic [raised, thick, red] scarring, and this [helps prevent both with] a tension-free closure. Reconnecting each tissue layer that was cut, from the bottom up, also keeps the skin from sticking down to the fascia and creating tethered scars (like those seen after C-sections)

doi: 10.1097/00000658-195903000-00011

For example, GSH forms thioether conjugates with leukotrienes, prostaglandins, hepoxilin, nitric oxide, hydroxyalkenals, ascorbic acid, dopa, dopamine, and maleic acid, and it forms thioesters with cysteine, coenzyme A, proteins, and other cellular thiols (Table 1 and Table 2)