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This free radical-mediated damage is considered as the initial pathogenic event in degeneration of melanocyte in generalized vitiligo and supplementing glutathione, which is a potent antioxidant, in vitiligo patients may prove to have therapeutic effect

Abnormalities in iron metabolism have serious implications for neuronal degenerative changes and brain dysfunction in AD

Maintenance phase: Once the loading phase is complete, patients transition to maintenance therapy with 1 mg hydroxocobalamin intramuscularly every two to three months for life

Most clinicians can manage this with a short follow-up and simple lab checks