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Additional illustrative linker intermediates (also referred as folate spacers) are described herein: EC 014 EC0014: 1H NMR (D 2 0, 500 MHz) 5(ppm) 8.73(s, IH, FA H-7), 7.56 (d, 2H, FA H-12&H16), 6.73(d, 2H, FA H-13&H15), 4.45(m, 2H), 4.1(m, 2H), 3.61(d, 2H), 2.82(m, 3H), 2.74(dd, IH), 2.37(m, 2H), 2.18(m, IH), 2.09(m, 3H), 1.74(m, IH) EXAMPLE Pte-y-D-Glu- -Dap-Asp-Cys EC0020: MS (ESI, [M+H] + ) 746
Immunohistochemical staining Formalin-fixed kidneys were embedded in paraffin, and 4-m sections were cut by the Barts Cancer Institute Pathology Unit
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It has been reported that the consumption of LC can present some positive effects on healthy subjects by improving physical, mental, and cognitive functions, and also decreasing the feeling of fatigue in the elderly
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