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If you break out from them, its likely irritation or clogged pores.

In June 2025, the World Health Organization issued a medical product alert highlighting NAION as a potential risk associated with semaglutide-containing medicines (Ozempic, Wegovy, and Rybelsus)

(81) proved that a high-fiber diet contributes to the recovery of gut microbiota, increases the production of SCFA, mediates GPR43 or GPR109A, reduces the expression of inflammatory factors, and reduces the incidence of kidney injury in diabetic mice

This is especially critical for those with pre-existing kidney disease or taking additional medications affecting renal function