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In heart failure patients, iron deficiency is known to impair cardiac energetics (mitochondrial function) and exacerbate symptoms [377], highlighting the risk of overzealous iron removal

9 Even more typical amounts of sitting may impair sperm quality: a study in 254 men found those who routinely sat during 50% or more of their time at work had substantially more sperm DNA damage compared with men who sat less than 50% of the time at work

Verdict: Vitamin C is easier to use daily for immunity

[129-131] A phase I human trial found 6 g/day NAC completely protected against hematuria, which is a dose-limiting side effect of ifosfamide (an analogue of cyclophosphamide)