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After undisclosed rebates and discounts negotiated by insurers and pharmacy benefit managers, the net cost is estimated to be 50-80% lower, according to analysis covered in The New York Times.(16) For uninsured patients or those with high-deductible plans, out-of-pocket costs likely still approach the full list price.(17) Medicare enrollees also pay more since current federal law prohibits Medicare from covering medications for weight loss

It allows continued monitoring of the benefit/risk balance of the medicinal product

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They represented a population that is notoriously difficult to help