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De-escalation strategies in HER2positive early breast cancer (EBC): final analysis of the WSG-ADAPT HER2+/HR- phase II trial: efficacy, safety, and predictive markers for 12 weeks of neoadjuvant dual blockade with trastuzumab and pertuzumab +/- weekly paclitaxel

Temperature fluctuationssuch as leaving tirzepatide on the counter during preparation or in a warm carcan shorten its stability window

Both drugs are being developed by Novo Nordisk, likely reflecting a portfolio strategy: CagriSema as the first-to-market injectable combination, and amycretin as a follow-on oral option for patients who prefer pills

Ultrasonic radiation with frequencies above 20 kHz enhances the extraction of inorganic and organic substances using liquid solvents