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Key takeaways Phentermine and Vyvanse are both central nervous system stimulant medications that affect dopamine and norepinephrine, but phentermine is an appetite suppressant for weight loss while Vyvanse is primarily for the treatment of ADHD and binge-eating disorders

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Clinical data consistently shows that lean mass accounts for approximately 25 to 40 percent of total weight lost during GLP-1 receptor agonist therapy