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Increased mTOR activity conditions excessive keratinocyte proliferation and increased lipogenesis in sebocytes, ultimately leading to sebum overproduction (176, 177)

No, but the prescribing information for STRENSIQ states the following: Studies have shown that there is analytical interference between asfotase alfa and laboratory tests that utilize an alkaline phosphatase (ALP)-conjugated test system, rendering erroneous test results in patients treated with STRENSIQ. 3 To avoid erroneous test results, clinicians should inform laboratory personnel that the patient is being treated with asfotase alfa and discuss with a laboratory medical director the use of a testing platform that does not utilize an ALP-conjugated test system

Salazar R, Ureta-Zaartu MS, DEGRADATION OF ACID VIOLET 7 AND REACTIVE BLACK 5 IN WATER BY ELECTRO-FENTON AND PHOTO ELECTRO-FENTON BY (2012) J Chil Chem Soc 57:9991003