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This is the inactive form of vitamin B12 that requires the body to expend more energy to convert and remove a cyanide molecule than other forms of B12

In animal-model work, NNMT inhibition with 5-Amino-1MQ has been associated with changes in adipose-tissue mass, in NAD+ pool sizes (because NNMT consumes nicotinamide that would otherwise feed the NAD+ salvage pathway), and in methyl-donor dynamics (because NNMT consumes S-adenosylmethionine)

Aug 2020;53(4):637-650