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Research investigating the peptide's influence on interleukin-1 signal transduction demonstrated that Epithalon modulates ceramide-mediated signaling pathways involved in immune cell activation

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In contrast, in experimental autoimmune encephalomyelitis (EAE) models, exendin-4, liraglutide, and dulaglutide consistently attenuate inflammation and oxidative stress (81, 87, 182), reduce clinical severity, and improve motor outcomes (83), mediated by AMPK/SIRT1 activation and NLRP3 inhibition

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