Enfermedad de Wolman y trastorno por depsito de steres de colesterol: estas dos enfermedades de herencia autosmica recesiva (gen LIPA en el cromosoma 10q 22,2-22,3), son debidas a deficiencia de lipasa cida lisosomal, originando acmulo de steres de colesterol y triglicridos en la mayora de los tejidos
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