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Several are now underway including the REMODEL T1D trial (semaglutide and kidney disease in T1D) and the SURPASS-T1D phase 3 trials (tirzepatide in T1D) with results expected in the coming years

Common Side Effects Both medications cause primarily gastrointestinal effects: Saxenda common side effects: Nausea (39%) Diarrhea (21%) Constipation (19%) Vomiting (16%) Injection site reactions (14%) Headache (14%) Dyspepsia (10%) Semaglutide common side effects: Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (24%) Abdominal pain (20%) Headache (14%) Fatigue (11%) Side Effect Comparison Table Interpreting the Numbers Semaglutide appears to have higher rates of GI side effects in clinical trials

This means you likely won't see the scales change immediately

Proton pump inhibitors (PPIs) frequently lower stomach acid production, speeding up ulcer healing during medical intervention