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Cycle Guidelines Common Cagrilintide Research Cycle Lengths Approach Short cycle Duration 16 weeks Review Point Week 16 Notes Reaches maintenance just as titration completes Approach Standard cycle Duration 26-32 weeks Review Point Week 26 / 32 Notes Matches Phase 2 trial durations Approach Long cycle Duration 68 weeks Review Point Week 68 Notes Matches REDEFINE 1 and REDEFINE 2 endpoints Cycle length is a research planning choice, not a treatment recommendation

Results can be seen within a few weeks after starting the therapy, although this can vary based on individual patient characteristics and the specific peptide

Morosky S, Wells AI, Lemon K, Evans AS, Schamus S, Bakkenist CJ, et al