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Sodium handling also shifts on semaglutide because the medication influences aldosterone signaling, a hormone that regulates salt balance

The effect of once-weekly 1 mg doses of semaglutide on walking ability was investigated in patients with peripheral arterial disease and T2D in the recently completed STRIDE trial (NCT04560998)

Oral options If needles are a dealbreaker, orally disintegrating tirzepatide tablets , tirzepatide drops , and oral tirzepatide formats are emerging options