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Weight loss injections , primarily glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Wegovy) and liraglutide (Saxenda), have become increasingly popular for managing obesity

All three tirzepatide doses produced superior reductions in HbA1c and body weight, and participants on tirzepatide 15 mg lost roughly twice the body weight of those on semaglutide 1 mg

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[77] This suppression may create a rationale for melatonin supplementation in patients taking beta-blockers who experience sleep disturbances, though the optimal dosing and timing strategies in this population require further research