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Growth hormone peaks during deep sleep, and inadequate rest impairs insulin sensitivity, increases cortisol (which promotes fat storage), and reduces the bodys ability to recover from the metabolic stress of rapid weight loss
In rodent and cell work, NNMT knockdown or inhibition has been described as protecting against diet-induced weight gain and improving metabolic measures without reducing food intake [5] [6]
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That breadth is part of what has made it so popular in online performance and recovery communities, even though popularity and proof are not the same thing
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