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The evidence indicates that within the iron-rich, ROS-prone microenvironment of EMS, Erastin inhibits the system Xc transporter, depletes intracellular glutathione (GSH), and inactivates GPX4, thereby driving ferroptosis in ectopic endometrial stromal cells
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Kidney function Periodic blood tests to monitor kidney health
Indications: Obesity (BMI 30 kg/m) Overweight (BMI 27 kg/m) with weight-related comorbidities Should be used with dietary and physical activity interventions Contraindications: Hypersensitivity to semaglutide or excipients Pregnancy or breastfeeding Personal/family history of medullary thyroid carcinoma Diagnosis of MEN 2 Side Effects: Very common (10%) : Nausea, vomiting, diarrhea, constipation Common (110%) : Headache, dizziness, fatigue, reflux Less common/rare : Gallstones, pancreatitis, renal impairment Reports of suicidal ideation in post-market surveillance Each pen delivers 2.4 mg of semaglutide in 0.5 mL of clear, colorless solution
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