[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Salas A, Hernandez-Rocha C, Duijvestein M, Faubion W, McGovern D, Vermeire S, et al
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4 This mitigation is envisioned to be from the dual mechanistic mode of action on the central reward pathways and influence on the gut via delayed gastric emptying, leading to enhanced blood alcohol content and a spike in aversive acetaldehyde levels
Conversely, semaglutide, with strong cardiovascular outcomes and weight-loss efficacy, may be better suited for individuals with obesity, T2DM, or high cardiometabolic risk, where it can improve histology and provide extra-hepatic benefits through calorie reduction and glycemic control
