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Journal of Clinical Investigation NIH National Institute on Aging, Baltimore, MD

We don't even know how much melatonin is too much because those studies just haven't been done." -- If you liked this story, sign up for The Essential List newsletter a handpicked selection of features, videos and can't-miss news delivered to your inbox every Friday.

The pharmacology of this compound may be an effective approach to improve therapeutic outcomes without loss of tolerability

In the current study, we first show in a large multicenter cohort of primary malignant peripheral nerve sheath tumors and second in a series of primary and metastatic melanomas that complete loss of H3K27 trimethylation is not a reliable marker to distinguish malignant peripheral nerve sheath tumor from melanoma