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Immune cells that have infiltrated the subendothelium also release cytokines, which results in recruitment of more immune cells and LDL particles to the site

Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells

Understanding whether these metabolic changes contribute to inflammation, synovial hypertrophy and cartilage damage will provide a novel insight of the progression and perpetuation of RA and will provide new therapeutic approaches for clinical use

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