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SIRT1 is part of a family of proteins called sirtuins, known as longevity genes. It uses NAD+ as a fuel source to repair DNA, reduce inflammation, and improve stress resistance

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In the TMJ context, it promotes collagen remodeling of the articular disc and joint capsule, slowing age- and function-related degenerative changes

FIGURE 5 GPX2 is Associated With M2 Macrophages, Which Predicts Cancer Immune Heterogeneity Since glutathione pathway genes, including GPX2 , showed different expression levels in different stages of PAAD, we tried to predict immune heterogeneity based on gene expression profiles in PC at different stages