Collectively, our findings establish a novel link between the oncogene VRK2 and GSH synthesis metabolism, providing a molecular basis for developing stratified metabolic therapies for PC patients
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The discovery of BAPs can start by querying public and commercial databases of (i) WP-derived bioactive peptides (e.g., BIOPEP [192], AHTPDB [193], and milk bioactive peptide database (MBPDB) [194], just to mention a few), or (ii) pharmacological targets, such as metabolic enzymes (i.e., ACE, dipeptidyl peptidase-IV (DPP-IV), -glucosidase), or (iii) markers of health and chronic diseases (i.e., cytokine levels, blood sugar, cholesterolemia, and sarcopenia)
