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Women on semaglutide should also be aware that hormonal changes during weight loss can affect menstrual cycles and energy levels, which may further complicate protein intake adherence

Many women report reduced anxiety and improved mood after starting treatment, partly from the weight loss itself and partly from the direct neurological effects of GLP-1 receptor activation on mood-regulating brain circuits

Tirzepatide produced greater average weight and waist reduction, while gastrointestinal adverse events were most common with both medications and were generally mild to moderate

Inclusion of Hypoglycemia in Clinical Practice Guidelines and Performance Measures in the Care of Patients With Diabetes