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Telomeres are the protective caps at the ends of chromosomes that shorten with each cell division critically short telomeres trigger cellular senescence, the state in which cells stop dividing and start secreting inflammatory signals that degrade surrounding tissue

These observations strengthen the evidence for a defective antioxidant system as an early pathophysiological change associated with the disease, rather than a sequela of drug effects, chronic disease and smoking (Reddy et al

In the same way, polydopamine (pDA) coating on the surface of particles can induce immobilization of some serum adhesives and adsorption of some cell types [52]

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