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The protein undergoes tyrosine phosphorylation at several sites and then binds to and activates phosphatidylinositol-3'-OH kinase and several other proteins containing src homology domains domains
CJC 1295 with DAC (Drug Affinity Complex) adds a lysine-linked maleimide group that covalently binds circulating albumin, extending the half-life to approximately 6 to 8 days and creating a non-pulsatile, sustained GH elevation that is physiologically quite different from normal secretion patterns
F.AzziJ.CravediP.RiellaL
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