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Beyond the liver, alcohol administration disturbs lipid homeostasis within adipose tissue, triggering a pathological flux of FFA from peripheral fat depots to the liver (Zhong et al., 2012
Our data showed that loss of Gclc decreased glucose flux into the TCA cycle (Fig
Thus, macrophage ferroptosis and macrophage-derived foam cell ferroptosis persist throughout plaque formation and progression to advanced unstable plaques
Since pesticide metabolism and inflammatory sensitivity can exhibit sex-dependent differences, future studies incorporating female cohorts are warranted to comprehensively evaluate the gender-specific risks of these fungicides
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