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Orlistat was linked to hepatotoxicity and adverse gastrointestinal events, sibutramine was associated with cardiovascular safety concerns, and lorcaserin was pulled from the market due to increased cancer risk
Saxenda (2014) was processed in three months for the same reason
The timeline to get from idea to the clinic is way shorter than it ever used to be. The companys discovery arm, which Pingle heads, focuses on reducing cycle time, the span from molecule design to data return, by co-locating synthesis, biology and testing on the same campus
A product must be formulated carefully to enable sufficient delivery to the skin, Dr
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