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PloS One (2019) 14:e0216711

Arrhythmia may result from a heart defect present since birth, the use of certain drugs and medications, or as a consequence of damage to the hearts muscular or electrical system due to heart failure, heart attack, high blood pressure, coronary heart disease, thyroid abnormalities, or rheumatic heart disease

If I was prescribing these medications today - in the informed consent discussion I would include the potential for modest outcomes, potentially increased psychiatric side effects, the general potential for side effects, and why outcomes may be variable

Bochynska, A., Lscher-Firzlaff, J