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These results may be compared with those of a post hoc analysis of the LEADER trial, which demonstrated similar incidence rates of MACE in the liraglutide vs placebo group in subjects with a relatively low baseline CV risk (defined as isolated CKD, hypertension with left ventricular hypertrophy, New York Heart Association Class II or III heart failure, and left ventricular systolic or diastolic dysfunction) [37]

Additional anti-diabetic use and rescue medication use reported in PIONEER 9 and 10 is summarized in Table 29

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