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The STEP 1 trial demonstrated a mean body weight reduction of 14.9% at this dose after 68 weeks, with 86.4% of participants achieving at least 5% weight loss and 69 to 79% achieving 10% or more

Carnitine supplements can cause nausea, vomiting, abdominal cramps, diarrhea, a fishy body odor, as well as a few other health risks, including an increased risk of CVD (especially in vegans or vegetarians)

Protocol execution Week 1-2: Begin loading phase

Although our previous study of D2R-DAT interaction was conducted in mouse tissues, we have confirmed the existence of D2R-DAT interaction using rat striatal tissue and that TAT-DAT NT peptide was able to disrupt the D2R-DAT interaction in this study (Fig