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Tirzepatide is the active pharmaceutical ingredient that has helped thousands of people lose and maintain weight loss in combination with diet and exercise

Materials Availability Reagents or materials used in this work may be requested from the Lead Contact by signing a completed material transfer agreement

Laboratory studies demonstrate that elimination of senescent cells through FOXO4-DRI administration can break the cycle of senescence induction and chronic inflammation, offering insights into interventions for age-related cellular dysfunction and tissue deterioration

In addition, it is used for the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver fibrosis in adults