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Human germline mutations in glutarate metabolism highlight its fundamental biological role, with loss of function mutations in glutaryl-CoA dehydrogenase (GCDH) resulting in glutarate accumulation and glutaric aciduria type 1 (GA1)a rare autosomal disorder characterized by dystonia, developmental delay and often death in early childhood 10

doi: 10.3390/nu13020615 43 RafeeqHAhmadSTareenMBKShahzadKABashirAJabeenRet al

(92) first proposed this concept, finding that high-fat diet mice exhibited significantly elevated plasma LPS levels accompanied by increased Gram-negative bacteria proportions and enhanced intestinal permeability

Formal drug interaction studies don't exist for BPC-157 in humans