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It differs from IGF-1 by additional 13 amino acids at the N-terminus and the substitution of arginine with glutamic acid at the 3rd position

Further, the role of GSH supplementation in stress protection as well as technological and health implications of microbial GSH metabolism are also discussed

Furthermore, the higher level of intracellular ROS may damage the mitochondrial membrane and the electron-transport chain, leading to the more ROS and amplifying the oxidative imbalance, also referred to as ROS-induced ROS release (Zorov et al., 2014