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Nat Rev Nephrol 17:417433 Ye Y, Chen A, Li L, Liang Q, Wang S, Dong Q (2022) Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification

Abstract Nephrolithiasis is a prevalent urological disorder in which calcium oxalate (CaOx) stones are most common, and accumulating evidence suggests that oxidative stress and ferroptosis contribute to CaOx-induced tubular epithelial injury

Acsl4 fl/fl mice were obtained from Cyagen Biosciences (Jiangsu), and Fsp1 fl/fl mice and Ksp Cre-ERT2 mice were sourced from GemPharmatech (Jiangsu)